Alpha-blockers are medicines used to manage and treat high blood pressure, also known as Hypertension.
In addition, they are used to prevent, treat or improve the symptoms of Benign Prostatic Hyperplasia (BPH).
Doctors sometimes prescribe them to treat certain types of tumors.
Alpha blockers have either a short or long duration of action.
Short-acting Alpha-blockers are effective immediately, but their effects only last a few hours....
Long-acting Alpha-blockers take longer to take action, but their effects are longer-lasting.
Alpha blockers are also known as:
- Alpha-adrenergic blocking agents
- Alpha-adrenergic antagonists
- Adrenergic blocking agents
- Alpha-blocking medications
What are the uses of Alpha blockers?
Uses in the Alpha blockers list include the management and treatment of Hypertension, Benign Prostatic Hyperplasia, and certain types of tumors (Pheochromocytoma).
High blood pressure (Hypertension)
High blood pressure, often known as Hypertension, happens when blood constantly pushes forcefully against the walls of blood vessels.
It leads to the condition where blood pressure is above normal levels.
Some FDA-approved Alpha blockers that are prescribed to people suffering from Hypertension are:
Benign Prostatic Hyperplasia (BPH)
Benign Prostatic Hyperplasia (BPH) is a prostate gland enlargement that is a common condition as men get older.
An enlarged prostate gland can result in unpleasant urinary symptoms, such as frequent urination, dribbling urine, obstruction of urine flow from the bladder, etc.
It can also cause difficulties with the bladder, urinary tract, and kidneys.
Some approved Alpha blockers for BPH are:
Pheochromocytoma is a rare disorder that is often a non-cancerous (benign) adrenal gland tumor.
If you have a pheochromocytoma, the tumor may release hormones that induce high blood pressure, headache, sweating, and panic attack symptoms.
How do Alpha-Blockers work?
Hypertension: Alpha-blockers function by inhibiting the method by which some cells in the body receive instructions.
They accomplish this by inhibiting alpha-receptors, which are located on cells in specific bodily locations or organs.
These receptors instruct their cells when to contract, constrict, or squeeze.
By inhibiting these receptors, these cells remain relaxed.
Due to the fact that many of these cells line the blood vessels and regulate the size of the blood vessels, keeping them relaxed reduces blood pressure.
Prostate Gland Enlargement: Some types of Alpha blockers also cause the relaxation of smooth muscle in the prostate, which allows urine to flow more freely via the urethra.
This process makes Alpha blockers for BPH an effective medicine.
Pheochromocytoma: Alpha-blockers are given preoperatively for a few weeks to neutralize the effects of the excess hormones secreted by the Pheochromocytoma.
This helps in lowering the frequency and severity of harmful intraoperative and postoperative blood pressure swings.
Side effects of Alpha blockers
When you begin using an Alpha blocker, you may experience low blood pressure and dizziness. Consequently, the first dose is frequently taken before bed.
Other possible adverse effects include:
- Pounding Heartbeat
- Blurred vision
Before taking an Alpha blocker, ensure that your physician is aware of any other medications you are taking, such as beta-blockers, calcium channel blockers, Erectile Dysfunction medications, Vitamin C, etc.
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