Natclovir 500 mg Injection

What Is Natclovir 500mg Injection?

Natclovir 500mg Injection is an antiviral medication prescribed to treat viral infections caused by cytomegalovirus(CMV) in immunocompromised people(who have undergone an organ or bone marrow transplantation).

The injection also lowers the risk of blindness in a severe eye infection because of CMV, also known as CMV retinitis. It is always recommended to administer the Natclovir 500mg Injection by a medical healthcare specialist. 

The injection is given by a slow intravenous(IV) infusion over one hour to avoid kidney damage. It is recommended to drink plenty of water during the treatment with Natclovir 500mg Injection. This will help you keep hydrated and will also prevent your kidney from any damage.

Vomiting, nausea, and increased liver enzymes are common side effects a person experiences while getting treated with Natclovir 500mg. You may experience symptoms at the injection site, such as pain, swelling, or redness. Tell your doctor if these symptoms persist for a longer duration. In case you are planning to get pregnant, conceiving, or breastfeeding, consult with the doctor first before taking the injection.

What Exactly Natclovir 500mg Injection Used For?

Natclovir 500mg Injection helps in treating viral infections, such as cytomegalovirus(CMV).

Cytomegalovirus Infection: It is a common herpes virus infection with a wide range of symptoms, starting with no symptoms to fever and fatigue, ending up with severe complications in the eye, brain, or other internal organs.

The infection can spread through sexual and nonsexual contact with body secretions in immunocompromised people or those who have undergone any transplantation. The injection comes under an antiviral group of medication, and thus it also helps by preventing the infection from multiplying.

Never self administer the injection, always take it with the help of medical officials. Do follow the instructions of the doctor.

Who Manufactures Natclovir 500mg Injection?

Natco Pharma Ltd is an Indian pharmaceutical company based in Hyderabad that manufactures Natclovir 500mg Injection. The company manufactures finished dosage formulations and active pharmaceutical ingredients.

Natco Pharma Ltd is considered the market leader in India's branded oncology medicines and among the country's top three producers of hepatitis C drugs. 

What Is The Strength Of Natclovir 500mg Injection?

The strength of medicine means the number of chemical components present in unit injection of the medicine. Here the strength of Natclovir injection is 500mg, which means 500mg of Ganciclovir is present in the unit injection of Natclovir.

The medicine is available in other multiple strengths and forms, such as:-

• Natclovir 500mg Injection
• Natclovir 250 mg injection
• Natclovir 250 mg capsules

What Are The Side Effects Of Natclovir 500mg Injection?

Along with some necessary side effects of the drug, some unwanted side effects are associated with it. But these unwanted side effects will only occur when you do not follow the instructions of the doctor.

Cross-check your symptoms with the list given below:-

More common

For oral capsules and injection into the vein, only

• Sore throat
• Fever
• Uncertain bleeding or bruising

Less common

For oral capsules and injection into the vein, only

• Mood or other mental changes
• Nervousness
• Pain at the place of injection
• Skin rash
• Tremor
• Unusual tiredness and weakness

For injection into the eye only

• Decreased vision or any change in vision

Some of the side effects do not require immediate medical treatment to get cured. Sometimes they get resolved on their own; such side effects are as follows:-

Less common

• Abdominal or stomach pain
• Loss of appetite
• Nausea and vomiting

What Drugs Show Interactions With Natclovir 500 mg Injection?

There is a total of 209 known drugs that show interactions with Ganciclovir(Natclovir 500 mg Injection), but the most frequent ones are as follows:-

• Augmentin (amoxicillin / clavulanate)
• Bactrim (sulfamethoxazole / trimethoprim)
• BuSpar (buspirone)
• Cipro (ciprofloxacin)
• Co-trimoxazole (sulfamethoxazole / trimethoprim)
• Cotrim (sulfamethoxazole / trimethoprim)
• Demerol (meperidine)
• Epogen (epoetin alfa)
• Heparin Sodium (heparin)
• Lasix (furosemide)
• Lexapro (escitalopram)
• Neupogen (filgrastim)
• Neurontin (gabapentin)
• Nubain (nalbuphine)
• Paracetamol (acetaminophen)
• Prograf (tacrolimus)
• Solu-Medrol (methylprednisolone)
• Synthroid (levothyroxine)
• Valcyte (valganciclovir)
• Zofran (ondansetron)

Does Diseases Also Interact With Natclovir 500mg Injection?

Yes, there are a total of 3 known disease interactions with Ganciclovir(Natclovir 500 mg Injection), such as:-

• Bone marrow suppression
• Renal dysfunction
• Hemodialysis

How To Administer Natclovir 500 mg Injection?

Natclovir 500 mg ‌‌is‌‌ ‌‌a‌‌ ‌‌high‌‌ ‌‌caution‌‌ ‌‌advised‌‌ ‌‌medicine‌‌ ‌‌and‌‌ ‌‌should‌‌ ‌‌only‌‌ ‌‌be‌‌ ‌‌injected‌‌ ‌‌by‌‌ ‌‌medical‌‌ ‌professionals.‌‌ ‌‌Do‌‌ ‌‌not‌‌ ‌‌take‌‌ ‌‌medicine‌‌ ‌‌on‌‌ ‌‌your‌‌ ‌‌own.‌‌ ‌‌Always‌‌ ‌‌take‌‌ ‌‌the‌‌ ‌‌help‌‌ ‌‌of‌‌ ‌‌your‌‌ ‌‌doctor.‌‌ ‌‌‌ ‌

List Of Precautions While Taking Natclovir 500 mg

Here is a list of points to be kept in mind while getting treated with Natclovir 500 mg, such as:-

• Do‌‌ ‌‌not‌‌ ‌‌consume‌‌ ‌‌alcohol‌‌ ‌‌while‌‌ ‌‌treating‌‌ ‌‌with‌‌ ‌‌Natclovir 500 mg ‌even‌ ‌though‌ ‌it‌ ‌does‌ ‌not‌ significantly‌ ‌impact‌ ‌consumption.‌‌ ‌‌In‌‌ ‌‌case‌‌ ‌‌of‌‌ ‌‌such‌‌ ‌‌situations,‌‌ ‌‌do‌‌ ‌‌consult‌‌ ‌‌with‌‌ ‌‌the‌‌ ‌‌doctor.‌‌ ‌‌‌ ‌

• Natclovir 500 mg ‌‌is‌‌ ‌‌unsafe‌‌ ‌‌for‌‌ ‌‌expecting‌‌ ‌‌women‌‌ ‌‌as‌‌ ‌‌limited‌‌ ‌‌information‌‌ ‌‌is‌‌ ‌‌available‌‌ ‌‌in‌‌ ‌‌this‌‌ ‌case.‌‌ ‌‌‌ ‌

• Do‌‌ ‌‌not‌‌ ‌‌inject‌‌ ‌‌Natclovir 500 mg ‌‌during‌‌ ‌‌breastfeeding,‌‌ ‌‌it‌‌ ‌‌can‌‌ ‌‌affect‌‌ ‌‌the‌‌ ‌‌growth‌‌ ‌‌of‌‌ ‌‌the‌‌ ‌‌baby.‌‌ ‌‌‌ ‌

• Natclovir 500 mg ‌‌may‌‌ ‌‌cause‌‌ ‌‌some‌‌ ‌‌effects‌‌ ‌‌that‌‌ ‌‌interfere‌‌ ‌‌with‌‌ ‌‌physical‌‌ ‌‌activities,‌‌ ‌‌such‌‌ ‌‌as‌‌ ‌driving.‌‌ ‌‌Therefore,‌‌ ‌‌do‌‌ ‌‌not‌‌ ‌‌go‌‌ ‌‌for‌‌ ‌‌a‌‌ ‌‌drive‌‌ ‌‌after‌‌ ‌‌injecting‌‌ ‌‌Natclovir 500 mg.‌‌ ‌‌‌ 

• People‌‌ ‌‌with‌‌ ‌‌kidney‌‌ ‌‌and‌‌ ‌‌liver‌‌ ‌‌complications‌‌ ‌‌need‌‌ ‌‌to‌‌ ‌‌inject‌‌ ‌‌the‌‌ ‌‌medicine‌‌ ‌‌with‌‌ ‌‌cautions.‌‌ ‌Thus,‌‌ ‌‌consult‌‌ ‌‌with‌‌ ‌‌the‌‌ ‌‌doctor‌‌ ‌‌first‌‌ ‌‌if‌‌ ‌‌you‌‌ ‌‌fall‌‌ ‌‌under‌‌ ‌‌this‌‌ ‌‌condition.‌‌ ‌‌‌ ‌

What Should I Do In Case Of Overdose Of The Natclovir 500 mg?

Overdose‌‌ ‌‌of‌‌ ‌ Natclovir 500 mg ‌‌can‌‌ ‌‌lead‌‌ ‌‌to‌‌ ‌‌nausea, vomiting, diarrhea, loss of appetite, and weakness.‌‌ ‌‌If‌‌ ‌‌you‌‌ ‌‌experience‌‌ ‌‌any‌‌ ‌‌of‌‌ ‌‌these‌‌ ‌‌frequently,‌‌ ‌‌seek‌‌ ‌‌immediate‌‌ ‌medical‌‌ ‌‌help.‌‌ ‌‌Even‌‌ ‌‌if‌‌ ‌‌you‌‌ ‌‌miss‌‌ ‌‌a‌‌ ‌‌dose,‌‌ ‌‌consult‌‌ ‌‌with‌‌ ‌‌the‌‌ ‌‌doctor,‌‌ ‌‌do‌‌ ‌‌not‌‌ ‌‌take‌‌ ‌‌it‌‌ ‌‌on‌‌ ‌‌your‌‌ ‌‌own.‌‌ 

How Should I Store Natclovir 500 mg Injection?

Keep‌‌ ‌‌the‌‌ ‌‌medicine‌‌ ‌‌at‌‌ ‌‌room‌‌ ‌‌temperature‌‌ ‌‌below‌‌ ‌‌30℃,‌‌ ‌‌and‌‌ ‌‌away‌‌ ‌‌from‌‌ ‌‌the‌‌ ‌‌light,‌‌ ‌‌moisture,‌‌ ‌‌and‌‌ ‌‌children.‌‌ ‌‌Do‌‌ ‌‌not‌‌ ‌‌forget‌‌ ‌‌to‌‌ ‌‌dispose‌‌ ‌‌of‌‌ ‌‌the‌‌ ‌‌drug‌‌ ‌‌properly.‌‌